Archives For R&D

Geoffrey A. Manne is Executive Director of the International Center for Law & Economics

Dynamic versus static competition

Ever since David Teece and coauthors began writing about antitrust and innovation in high-tech industries in the 1980s, we’ve understood that traditional, price-based antitrust analysis is not intrinsically well-suited for assessing merger policy in these markets.

For high-tech industries, performance, not price, is paramount — which means that innovation is key:

Competition in some markets may take the form of Schumpeterian rivalry in which a succession of temporary monopolists displace one another through innovation. At any one time, there is little or no head-to-head price competition but there is significant ongoing innovation competition.

Innovative industries are often marked by frequent disruptions or “paradigm shifts” rather than horizontal market share contests, and investment in innovation is an important signal of competition. And competition comes from the continual threat of new entry down the road — often from competitors who, though they may start with relatively small market shares, or may arise in different markets entirely, can rapidly and unexpectedly overtake incumbents.

Which, of course, doesn’t mean that current competition and ease of entry are irrelevant. Rather, because, as Joanna Shepherd noted, innovation should be assessed across the entire industry and not solely within merging firms, conduct that might impede new, disruptive, innovative entry is indeed relevant.

But it is also important to remember that innovation comes from within incumbent firms, as well, and, often, that the overall level of innovation in an industry may be increased by the presence of large firms with economies of scope and scale.

In sum, and to paraphrase Olympia Dukakis’ character in Moonstruck: “what [we] don’t know about [the relationship between innovation and market structure] is a lot.”

What we do know, however, is that superficial, concentration-based approaches to antitrust analysis will likely overweight presumed foreclosure effects and underweight innovation effects.

We shouldn’t fetishize entry, or access, or head-to-head competition over innovation, especially where consumer welfare may be significantly improved by a reduction in the former in order to get more of the latter.

As Katz and Shelanski note:

To assess fully the impact of a merger on market performance, merger authorities and courts must examine how a proposed transaction changes market participants’ incentives and abilities to undertake investments in innovation.

At the same time, they point out that

Innovation can dramatically affect the relationship between the pre-merger marketplace and what is likely to happen if the proposed merger is consummated…. [This requires consideration of] how innovation will affect the evolution of market structure and competition. Innovation is a force that could make static measures of market structure unreliable or irrelevant, and the effects of innovation may be highly relevant to whether a merger should be challenged and to the kind of remedy antitrust authorities choose to adopt. (Emphasis added).

Dynamic competition in the ag-biotech industry

These dynamics seem to be playing out in the ag-biotech industry. (For a detailed look at how the specific characteristics of innovation in the ag-biotech industry have shaped industry structure, see, e.g., here (pdf)).  

One inconvenient truth for the “concentration reduces innovation” crowd is that, as the industry has experienced more consolidation, it has also become more, not less, productive and innovative. Between 1995 and 2015, for example, the market share of the largest seed producers and crop protection firms increased substantially. And yet, over the same period, annual industry R&D spending went up nearly 750 percent. Meanwhile, the resulting innovations have increased crop yields by 22%, reduced chemical pesticide use by 37%, and increased farmer profits by 68%.

In her discussion of the importance of considering the “innovation ecosystem” in assessing the innovation effects of mergers in R&D-intensive industries, Joanna Shepherd noted that

In many consolidated firms, increases in efficiency and streamlining of operations free up money and resources to source external innovation. To improve their future revenue streams and market share, consolidated firms can be expected to use at least some of the extra resources to acquire external innovation. This increase in demand for externally-sourced innovation increases the prices paid for external assets, which, in turn, incentivizes more early-stage innovation in small firms and biotech companies. Aggregate innovation increases in the process!

The same dynamic seems to play out in the ag-biotech industry, as well:

The seed-biotechnology industry has been reliant on small and medium-sized enterprises (SMEs) as sources of new innovation. New SME startups (often spinoffs from university research) tend to specialize in commercial development of a new research tool, genetic trait, or both. Significant entry by SMEs into the seed-biotechnology sector began in the late 1970s and early 1980s, with a second wave of new entrants in the late 1990s and early 2000s. In recent years, exits have outnumbered entrants, and by 2008 just over 30 SMEs specializing in crop biotechnology were still active. The majority of the exits from the industry were the result of acquisition by larger firms. Of 27 crop biotechnology SMEs that were acquired between 1985 and 2009, 20 were acquired either directly by one of the Big 6 or by a company that itself was eventually acquired by a Big 6 company.

While there is more than one way to interpret these statistics (and they are often used by merger opponents, in fact, to lament increasing concentration), they are actually at least as consistent with an increase in innovation through collaboration (and acquisition) as with a decrease.

For what it’s worth, this is exactly how the startup community views the innovation ecosystem in the ag-biotech industry, as well. As the latest AgFunder AgTech Investing Report states:

The large agribusinesses understand that new innovation is key to their future, but the lack of M&A [by the largest agribusiness firms in 2016] highlighted their uncertainty about how to approach it. They will need to make more acquisitions to ensure entrepreneurs keep innovating and VCs keep investing.

It’s also true, as Diana Moss notes, that

Competition maximizes the potential for numerous collaborations. It also minimizes incentives to refuse to license, to impose discriminatory restrictions in technology licensing agreements, or to tacitly “agree” not to compete…. All of this points to the importance of maintaining multiple, parallel R&D pipelines, a notion that was central to the EU’s decision in Dow-DuPont.

And yet collaboration and licensing have long been prevalent in this industry. Examples are legion, but here are just a few significant ones:

  • Monsanto’s “global licensing agreement for the use of the CRISPR-Cas genome-editing technology in agriculture with the Broad Institute of MIT and Harvard.”
  • Dow and Arcadia Biosciences’ “strategic collaboration to develop and commercialize new breakthrough yield traits and trait stacks in corn.”
  • Monsanto and the University of Nebraska-Lincoln’s “licensing agreement to develop crops tolerant to the broadleaf herbicide dicamba. This agreement is based on discoveries by UNL plant scientists.”

Both large and small firms in the ag-biotech industry continually enter into new agreements like these. See, e.g., here and here for a (surely incomplete) list of deals in 2016 alone.

At the same time, across the industry, new entry has been rampant despite increased M&A activity among the largest firms. Recent years have seen venture financing in AgTech skyrocket — from $400 million in 2010 to almost $5 billion in 2015 — and hundreds of startups now enter the industry annually.

The pending mergers

Today’s pending mergers are consistent with this characterization of a dynamic market in which structure is being driven by incentives to innovate, rather than monopolize. As Michael Sykuta points out,

The US agriculture sector has been experiencing consolidation at all levels for decades, even as the global ag economy has been growing and becoming more diverse. Much of this consolidation has been driven by technological changes that created economies of scale, both at the farm level and beyond.

These deals aren’t fundamentally about growing production capacity, expanding geographic reach, or otherwise enhancing market share; rather, each is a fundamental restructuring of the way the companies do business, reflecting today’s shifting agricultural markets, and the advanced technology needed to respond to them.

Technological innovation is unpredictable, often serendipitous, and frequently transformative of the ways firms organize and conduct their businesses. A company formed to grow and sell hybrid seeds in the 1920s, for example, would either have had to evolve or fold by the end of the century. Firms today will need to develop (or purchase) new capabilities and adapt to changing technology, scientific knowledge, consumer demand, and socio-political forces. The pending mergers seemingly fit exactly this mold.

As Allen Gibby notes, these mergers are essentially vertical combinations of disparate, specialized pieces of an integrated whole. Take the proposed Bayer/Monsanto merger, for example. Bayer is primarily a chemicals company, developing advanced chemicals to protect crops and enhance crop growth. Monsanto, on the other hand, primarily develops seeds and “seed traits” — advanced characteristics that ensure the heartiness of the seeds, give them resistance to herbicides and pesticides, and speed their fertilization and growth. In order to translate the individual advances of each into higher yields, it is important that these two functions work successfully together. Doing so enhances crop growth and protection far beyond what, say, spreading manure can accomplish — or either firm could accomplish working on its own.

The key is that integrated knowledge is essential to making this process function. Developing seed traits to work well with (i.e., to withstand) certain pesticides requires deep knowledge of the pesticide’s chemical characteristics, and vice-versa. Processing huge amounts of data to determine when to apply chemical treatments or to predict a disease requires not only that the right information is collected, at the right time, but also that it is analyzed in light of the unique characteristics of the seeds and chemicals. Increased communications and data-sharing between manufacturers increases the likelihood that farmers will use the best products available in the right quantity and at the right time in each field.

Vertical integration solves bargaining and long-term planning problems by unifying the interests (and the management) of these functions. Instead of arm’s length negotiation, a merged Bayer/Monsanto, for example, may better maximize R&D of complicated Ag/chem products through fully integrated departments and merged areas of expertise. A merged company can also coordinate investment decisions (instead of waiting up to 10 years to see what the other company produces), avoid duplication of research, adapt to changing conditions (and the unanticipated course of research), pool intellectual property, and bolster internal scientific capability more efficiently. All told, the merged company projects spending about $16 billion on R&D over the next six years. Such coordinated investment will likely garner far more than either company could from separately spending even the same amount to develop new products. 

Controlling an entire R&D process and pipeline of traits for resistance, chemical treatments, seeds, and digital complements would enable the merged firm to better ensure that each of these products works together to maximize crop yields, at the lowest cost, and at greater speed. Consider the advantages that Apple’s tightly-knit ecosystem of software and hardware provides to computer and device users. Such tight integration isn’t the only way to compete (think Android), but it has frequently proven to be a successful model, facilitating some functions (e.g., handoff between Macs and iPhones) that are difficult if not impossible in less-integrated systems. And, it bears noting, important elements of Apple’s innovation have come through acquisition….


As LaFontaine and Slade have made clear, theoretical concerns about the anticompetitive consequences of vertical integrations are belied by the virtual absence of empirical support:

Under most circumstances, profit–maximizing vertical–integration and merger decisions are efficient, not just from the firms’ but also from the consumers’ points of view.

Other antitrust scholars are skeptical of vertical-integration fears because firms normally have strong incentives to deal with providers of complementary products. Bayer and Monsanto, for example, might benefit enormously from integration, but if competing seed producers seek out Bayer’s chemicals to develop competing products, there’s little reason for the merged firm to withhold them: Even if the new seeds out-compete Monsanto’s, Bayer/Monsanto can still profit from providing the crucial input. Its incentive doesn’t necessarily change if the merger goes through, and whatever “power” Bayer has as an input is a function of its scientific know-how, not its merger with Monsanto.

In other words, while some competitors could find a less hospitable business environment, consumers will likely suffer no apparent ill effects, and continue to receive the benefits of enhanced product development and increased productivity.

That’s what we’d expect from innovation-driven integration, and antitrust enforcers should be extremely careful before thwarting or circumscribing these mergers lest they end up thwarting, rather than promoting, consumer welfare.

Diana L. Moss is President of the American Antitrust Institute

Innovation Competition in the Spotlight

Innovation is more and more in the spotlight as questions grow about concentration and declining competition in the U.S. economy. These questions come not only from advocates for more vigorous competition enforcement but also, increasingly, from those who adhere to the school of thought that consolidation tends to generate procompetitive efficiencies. On March 27th, the European Commission issued its decision approving the Dow-DuPont merger, subject to divestitures of DuPont’s global R&D agrichemical assets to preserve price and innovation competition.

Before we read too much into what the EU decision in Dow-DuPont means for merger review in the U.S., remember that agriculture differs markedly across regions. Europe uses very little genetically modified (or transgenic) seed, whereas row crop acreage in the U.S. is planted mostly with it. This cautions against drawing major implications of the EU’s decision across jurisdictions.

This post unpacks the mergers of Dow-DuPont and Monsanto-Bayer in the U.S. and what they mean for innovation competition.

A Troubled Landscape? Past Consolidation in Agricultural Biotechnology

If approved as proposed, the mergers of Dow-DuPont and Monsanto-Bayer would reduce the field of Big 6 agricultural biotechnology (ag-biotech) firms to the Big 4. This has raised concerns about potentially higher prices for traits, seeds, and agrichemicals, less choice, and less innovation. The two mergers would make a 3rd wave of consolidation in the industry since the mid-1980s, when transgenic technology first emerged. Past consolidation has materially affected the structure of the markets. This is particularly true in crop seed, where relative to other agricultural input sectors, the level of concentration (and increases in concentration) over time is the highest.

Growers and consumers feel the effects of these changes. Consumers pay attention to their choices at the grocery store, which have arguably diminished and for which they pay prices that have risen at rates in excess of inflation. And the states in which agriculture is a major economic activity worry about their growers and the prices they pay for transgenic seed, agrichemicals, and fertilizers. Farmers we spoke to note, for example, that weeds that are resistant to the herbicide Roundup have evolved over time, making it no longer as effective as it once was. Dependence on seed and chemical cropping systems with declining effectiveness (due to resistance) has been met by the industry with newer and more expensive traited seed and different agrichemicals. With consolidation, these alternatives have dwindled.

These are not frivolous concerns. Empirical evidence shows that “technology fees” on transgenic corn, soybean, and cotton seed make up a significant proportion of total seed costs. The USDA notes that the prices of farm inputs, led by crop seed, generally have risen faster over the last 20 years than the prices farmers have received for their commodities. Moreover, seed price increases have outpaced yield increases over time. And finally, the USDA has determined that increasing levels of concentration in agricultural input markets (including crop seed) are no longer generally associated with higher R&D or a permanent rise in R&D intensity.

Putting the Squeeze on Growers and Consumers

The “squeeze” on growers and consumers highlights the fact that ag-biotech innovation comes at an increasingly higher price – a price that many worry will increase if the Dow-DuPont and Monsanto-Bayer mergers go through. These concerns are magnified by the structure of the food supply chain where we see a lot of growers and consumers at either end but not a lot of competition in the middle. In the middle are the ag-biotech firms that innovate traits, seeds, and agrichemicals; food processors such as grain millers and meatpackers; food manufacturers; distributors; and retail grocers.

Almost every sector has been affected by significant consolidation over the last two decades, some of which has been blocked, but a lot of which has not. For example, U.S. antitrust enforcers stopped the mergers of beef packers JBS and National Beef and broadline food distributors Sysco and USFoods. But key mergers that many believed raised significant competitive concerns went through, including Tyson-Hillshire Brands (pork), ConAgra-Horizon Mills (flour), Monsanto-Delta & Pine Land (cotton), and Safeway-Albertsons (grocery).

Aside from concerns over price, quality, and innovation, consolidation in “hourglass” shaped supply chains raises other issues. For example, it is often motivated by incentives to bulk up to bargain more effectively vis-a-vis more powerful input suppliers or customers. As we have seen with health care providers and health insurers, mergers for this purpose can trigger further consolidation, creating a domino effect. A bottlenecked supply chain also decreases resiliency. With less competition, it is more exposed to exogenous shocks such as bioterrorism or food-borne disease. That’s a potential food security problem.

Innovation Competition and the Agricultural Biotechnology Mergers

The Dow-DuPont and Monsanto-Bayer merger proposals raise a number of issues. One is significant overlap in seed, likely to result in a duopoly in corn and soybeans and a dominant firm (Monsanto) in cotton. A second concern is that the mergers would create or enhance substantial vertical integration. Where some arguments for integration can carry weight in a Guidelines analysis, here there is economic evidence from soybeans and cotton indicating that prices tend to be higher under vertical integration than under cross-licensing arrangements.

Moreover, the “platforms” resulting from the mergers are likely to be engineered for the purpose of creating exclusive packages of traits, seeds, and agrichemicals that are less likely to interoperate with rival products. This could raise entry barriers for smaller innovators and reduce or cut off access to resources needed to compete effectively. Indeed, one farmer noted the constraint of being locked into a single traits-seeds-chemicals platform in a market with already limited competition “[I] can’t mix chemicals with other companies’ products to remedy Roundup resistance.”

A third concern raised by the mergers is the potential elimination of competition in innovation markets. The DOJ/FTC Horizontal Merger Guidelines (§6.4) note that a merger may diminish innovation competition through curtailment of “innovative efforts below the level that would prevail in the absence of the merger.” This is especially the case when the merging firms are each other’s close competitors (e.g., as in the DOJ’s case against Applied Materials and Tokyo Electron). Dow, DuPont, Monsanto, and Bayer are four of only six ag-biotech rivals.

Preserving Parallel Path R&D Pipelines

In contrast to arguments that the mergers would combine only complementary assets, the R&D pipelines for all four firms show overlaps in major areas of traits, seeds, and crop protection. This supports the notion that the R&D pipelines compete head-to-head for technology intended for commercialization in U.S. markets. Maintaining competition in R&D ensures incentives remain strong to continue existing and prospective product development programs. This is particularly true in industries like ag-biotech (and pharma) where R&D is risky, regulatory approvals take time, and commercial success depends on crop planning and switching costs.

Maintaining Pro-Competitive Incentives to Cross-License Traits

Perhaps more important is that innovation in ag-biotech depends on maintaining a field of rivals, each with strong pro-competitive incentives to collaborate to form new combined (i.e., “stacked”) trait profiles. Farmers benefit most when there are competing stacks to choose from. About 60% of all stacks on the market in 2009 were the result of joint venture cross-licensing collaborations across firms. And the traits innovated by Dow, DuPont, Monsanto, and Bayer account for over 80% of traits in those stacks. That these companies are important innovators is apparent in GM Crop Database data for genetic corn, soybean and cotton “events” approved in the U.S. From 1991-2014, for example, the four companies account for a significant proportion of innovation in important genetic events.

Competition maximizes the potential for numerous collaborations. It also minimizes incentives to refuse to license, to impose discriminatory restrictions in technology licensing agreements, or to tacitly “agree” not to compete. Such agreements could range from deciding which firms specialize in certain crops or traits, to devising market “rules,” such as cross-licensing terms and conditions. All of this points to the importance of maintaining multiple, parallel R&D pipelines, a notion that was central to the EU’s decision in Dow-DuPont.

Remedies or Not? Preserving Innovation Competition

The DOJ has permitted two major ag-biotech mergers in the last decade, Monsanto’s mergers with DeKalb (corn) and Delta & Pine Land (cotton). In crafting remedies in both cases, the DOJ recognized the importance of innovation markets by fashioning remedies that focused on licensing or divesting patented technologies. The proposed mergers of Dow-DuPont and Monsanto-Bayer appear to be a different animal. They would reduce an already small field of large, integrated competitors, raise competitive concerns that have more breadth and complexity than in previous mergers, and are superimposed on growing evidence that transgenic technology has come at a higher and higher a price.Add to this the fact that a viable buyer of any divestiture R&D asset would be difficult to find outside the Big 6. Such a buyer would need to be national, if not global, in scale and scope in order to compete effectively

Add to this the fact that a viable buyer of any divestiture R&D asset would be difficult to find outside the Big 6. Such a buyer would need to be national, if not global, in scale and scope in order to compete effectively post-merger. Lack of scale and scope in R&D, financing, marketing, and distribution would necessitate cobbling together a package of assets to create and potentially prop up a national competitor. While the EU managed to pull this off, it is unclear whether the fact pattern in the U.S. would support a similar outcome. What we do know is that past mergers in the food and agriculture space have squeezed growers and consumers. Unless adequately addressed, these mega-deals stand to squeeze them even more.

Levi A. Russell is Assistant Professor, Agricultural & Applied Economics, University of Georgia and a blogger at Farmer Hayek.

Though concentration seems to be an increasingly popular metric for discussing antitrust policy (a backward move in my opinion, given the theoretical work by Harold Demsetz and others many years ago in this area), contestability is still the standard for evaluating antitrust issues from an economic standpoint. Contestability theory, most closely associated with William Baumol, rests on three primary principles. A market is perfectly contestable if 1) new entrants are not at a cost disadvantage to incumbents, 2) there are no barriers to entry or exit, and 3) there are no sunk costs. In this post, I discuss these conditions in relation to recent mergers and acquisitions in the agricultural chemical and biotech industry.

Contestability is rightly understood as a spectrum. While no industry is perfectly contestable, we expect that markets in which barriers to entry or exit are low, sunk costs are low, and new entrants can easily produce at similar cost to incumbents would be more innovative and that prices would be closer to marginal costs than in other industries. Certainly the agricultural chemical and biotech space does not appear to be very contestable, given the conditions above. There are significant R&D costs associated with the creation of new chemistries and new seed traits. The production and distribution of these products are likely to be characterized by significant economies of scale. Thus, the three conditions listed above are not met, and indeed the industry seems to be characterized by very low contestability. We would expect, then, that these mergers and acquisitions would drive up the prices of the companies’ products, leading to higher monopoly profits. Indeed, one study conducted at Texas A&M University finds that, as a result of the Bayer-Monsanto acquisition and DuPont/Pioneer merger with Dow, corn, soybean, and cotton prices will rise by an estimated 2.3%, 1.9%, and 18.2%, respectively.

These estimates are certainly concerning, especially given the current state of the agricultural economy. As the authors of the Texas A&M study point out, these estimates provide a justification for antitrust authorities to examine the merger and acquisition cases further. However, our dependence on the contestability concept as it pertains to the real world should also be scrutinized. To do so, we can examine other industries in which, according to the standard model of contestability, we would expect to find high barriers to entry or exit, significant sunk costs, and significant cost disadvantages for incumbents.

This chart, assembled by the American Enterprise Institute using data from the Bureau of Labor Statistics, shows the changes in prices of several consumer goods and services from 1996 to 2016, compared with CPI inflation. Industries in which there are high barriers to entry or exit, significant sunk costs, and significant cost disadvantages for new entrants such as automobiles, wireless service, and TVs have seen their prices plummet relative to inflation over the 20 year period. There has also been significant product innovation in these industries over the time period.

Disallowing mergers or acquisitions that will create synergies that lead to further innovation or lower cost is not an improvement in economic efficiency. The transgenic seeds created by some of these companies have allowed farmers to use less-toxic pesticides, providing both private and public benefits. Thus, the higher prices projected by the A&M study might be justified on efficiency grounds. The R&D performed by these firms has led to new pesticide chemistries that have allowed farmers to deal with changes in the behavior of insect populations and will likely allow them to handle issues of pesticide resistance in plants and insects in the future.

What does the empirical evidence on trends in prices and the value of these agricultural firms’ innovations described above imply about contestability and its relation to antitrust enforcement? Contestability should be understood not as a static concept, but as a dynamic one. Competition, more broadly, is the constant striving to outdo competitors and to capture economic profit, not a set of conditions used to analyze a market via a snapshot in time. A proper understanding of competition as a dynamic concept leads us to the following conclusion: for a market to be contestable such that incumbents are incentivized to behave in a competitive manner, the cost advantages and barriers to entry or exit enjoyed by incumbents must be equal to or less than an entrepreneur’s expectation of economic profit associated with entry.  Thus, a commitment to property rights by antitrust courts and avoidance of excessive licensure, intellectual property, and economic regulation by the legislative and executive branches is sufficient from an economic perspective to ensure a reasonable degree of contestability in markets.

In my next post I will discuss a source of disruptive technology that will likely provide some competitive pressure on the firms in these mergers and acquisitions in the near future.